The influence of focal ischemic brain injury on tail-flick latency in the rat.

@article{Tsai1994TheIO,
  title={The influence of focal ischemic brain injury on tail-flick latency in the rat.},
  author={Y. C. Tsai and Sun-Jen Huang and C L Chang},
  journal={Acta anaesthesiologica Sinica},
  year={1994},
  volume={32 2},
  pages={115-20}
}
Tail-flick latency (TFL), a measure of response threshold to pain, was investigated in rats with focal ischemic brain injury resulting from middle cerebral artery occlusion (MCAO) as compared to sham and non-operative (non-op) groups on the 1st, 7th, 14th, 21st and 28th days following surgery or anesthesia. No significant differences were observed between MCAO and sham groups postoperatively, indicating focal ischemic insult induced by this model had no significant influence on TFL. Increased… CONTINUE READING