The influence of ferucarbotran on the chondrogenesis of human mesenchymal stem cells.

@article{Henning2009TheIO,
  title={The influence of ferucarbotran on the chondrogenesis of human mesenchymal stem cells.},
  author={Tobias D. Henning and Elizabeth J Sutton and Anne J. Kim and Daniel M. Golovko and Andrew E Horvai and Larry D. Ackerman and Barbara Sennino and D M Mcdonald and Jeffrey C. Lotz and Heike E. Daldrup-Link},
  journal={Contrast media & molecular imaging},
  year={2009},
  volume={4 4},
  pages={165-73}
}
For in vivo applications of magnetically labeled stem cells, biological effects of the labeling procedure have to be precluded. This study evaluates the effect of different ferucarbotran cell labeling protocols on chondrogenic differentiation of human mesenchymal stem cells (hMSC) as well as their implications for MR imaging. hMSC were labeled with ferucarbotran using various protocols: cells were labeled with 100 microg Fe/ml for 4 and 18 h and additional samples were cultured for 6 or 12 days… CONTINUE READING

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