The influence of extra-umbilical serotonin, PGE2 and PGF2 alpha on prostanoid production in human umbilical arteries.


The influence of extra-umbilical applications of serotonin and prostaglandins PGE2 and PGF2 alpha on the endogenous production of prostacyclin and thromboxane in human umbilical arteries was registered during in vitro perfusion by use of specific radio-immunoassays. PGE2 and PGF2 alpha caused significant dose-dependent increases in the production of… (More)


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