The influence of cytomegalovirus carrier status on lymphocyte subsets and natural immunity.

@article{Gratama1987TheIO,
  title={The influence of cytomegalovirus carrier status on lymphocyte subsets and natural immunity.},
  author={Jan Willem C. Gratama and M J M Tinie Kardol and Albert M I H Naipal and Jacqueline Slats and Andries den Ouden and Theo Stijnen and J. D'Amaro and T. Hauw The and J W Bruning},
  journal={Clinical and experimental immunology},
  year={1987},
  volume={69 1},
  pages={16-24}
}
The influence of the cytomegalovirus (CMV) carrier status on peripheral lymphocyte subsets was studied in 70 healthy individuals. IgG-class antibodies against CMV late antigen were used as markers for the presence of CMV in those individuals. The 39 CMV-seropositive individuals had significantly higher numbers of CD3+ (P = 0.009), CD8+ (P = 0.005) and HNK1+ (P = 0.002) cells than the 31 CMV-seronegative individuals. Two-colour immunofluorescence studies revealed that the HNK1+ cells… CONTINUE READING