The influence of combretastatin A-4 and vinblastine on interstitial fluid pressure in BT4An rat gliomas.

@article{Eikesdal2002TheIO,
  title={The influence of combretastatin A-4 and vinblastine on interstitial fluid pressure in BT4An rat gliomas.},
  author={Hans Petter Eikesdal and Willy Landuyt and Olav Dahl},
  journal={Cancer letters},
  year={2002},
  volume={178 2},
  pages={209-17}
}
The influence of combretastatin A-4 disodium phosphate (CA-4, 50mg/kg intraperitoneally (i.p.)) and vinblastine (2mg/kg i.p.) on interstitial fluid pressure (IFP) was assessed in BT4An rat gliomas implanted subcutaneously in the neck. Furthermore the growth inhibitory effect of vinblastine and the distribution of fluorescence-conjugated vinblastine (BODIPY-vinblastine) were investigated. Tumors at different volumes were compared. Whereas CA-4 had no major influence on IFP, independent of tumor… CONTINUE READING

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