The influence of capsaicin on membrane currents in dorsal root ganglion neurones of guinea-pig and chicken

@article{Petersen1987TheIO,
  title={The influence of capsaicin on membrane currents in dorsal root ganglion neurones of guinea-pig and chicken},
  author={Marlen Petersen and Fr. -K. Pierau and M. Weyrich},
  journal={Pfl{\"u}gers Archiv},
  year={1987},
  volume={409},
  pages={403-410}
}
The effect of capsaicin on voltage-dependent membrane currents of isolated dorsal root ganglia (DRG) neurones of guinea-pig and chicken were investigated by the voltage-clamp technique and intracellular perfusion. In both species, administration of capsaicin (3·10−5 M) to the outer surface of the cell membrane reduced the amplitude and accelerated the inactivation of the fast inactivating potassium current. In contrast, 3,4-diaminopyridine (3,4-DAP) reduced the fast potassium current without… CONTINUE READING

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