• Biology, Medicine
  • Published in Journal of applied genetics 2003

The influence of calyculin A on lymphocytes in vitro.

@article{Kowalska2003TheIO,
  title={The influence of calyculin A on lymphocytes in vitro.},
  author={Agata Kowalska and Małgorzata Srebniak and Angelika Wawrzkiewicz and Kazimierz Kamiński},
  journal={Journal of applied genetics},
  year={2003},
  volume={44 3},
  pages={
          413-8
        }
}
Human lymphocytes were cultured in vitro and treated with calyculin A. The aim of this work was to estimate the influence of calyculin A on chromosome morphology and banding patterns. It was also interesting whether calyculin A treatment is useful in cytogenetic analysis of human karyotype. We proved that calyculin A induces chromosome condensation in lymphocytes and raises the mitotic index significantly. Moreover, calyculin A does not influence the banding patterns. Therefore it is concluded… CONTINUE READING

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