The influence of breast size on late radiation effects and association with radiotherapy dose inhomogeneity.

@article{Moody1994TheIO,
  title={The influence of breast size on late radiation effects and association with radiotherapy dose inhomogeneity.},
  author={Anne Marie Moody and William Philip M. Mayles and Judith Margaret Bliss and Roger P A'hern and John R. Owen and Jane Regan and B Broad and John R. Yarnold},
  journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology},
  year={1994},
  volume={33 2},
  pages={106-12}
}
A prospective assessment of late changes in breast appearance in 559 patients after tumour excision and radiotherapy for early breast cancer noted a strong association with breast size. Only 3/48 (6%) patients with small breasts developed moderate or severe late changes compared with 94/423 (22%) with medium sized breasts and 34/88 (39%) patients with large breasts (p < 0.001). One possibility is that greater radiation changes are related to greater dose inhomogeneity in women with large… CONTINUE READING