The influence of beta-adrenoceptor blocking drugs with and without intrinsic sympathomimetic activity on the hormonal responses to hypo- and hyperglycaemia.

@article{Schlter1982TheIO,
  title={The influence of beta-adrenoceptor blocking drugs with and without intrinsic sympathomimetic activity on the hormonal responses to hypo- and hyperglycaemia.},
  author={K. J. Schl{\"u}ter and Walter H. Aellig and K. G. Petersen and H C Rieband and Adolf Wehrli and Lothar Kerp},
  journal={British journal of clinical pharmacology},
  year={1982},
  volume={13 Suppl 2},
  pages={
          407S-417S
        }
}
1 The effects of oral doses of pindolol (15 mg), metoprolol (200 mg) and propranolol (160 mg) on the response to insulin-induced hypoglycaemia and an oral glucose load were investigated. 2 Serum insulin and serum C-peptide secretion in response to a glucose load were inhibited (2P less than 0.01) by metoprolol and propranolol but not by pindolol. 3 During hypoglycaemia metoprolol and propranolol inhibited the clearance of insulin (2P less than 0.01) and caused a delay of glucose nadirs. 4… 
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