The influence of apolipoprotein E genotype on visuospatial attention dissipates after age 80.

@article{Negash2009TheIO,
  title={The influence of apolipoprotein E genotype on visuospatial attention dissipates after age 80.},
  author={Selam Negash and Pamela M. Greenwood and Trey P Sunderland and Raja Parasuraman and Yonas Endale Geda and David S. Knopman and Bradley F. Boeve and Robert J. Ivnik and Ronald C. Petersen and Glenn E. Smith},
  journal={Neuropsychology},
  year={2009},
  volume={23 1},
  pages={81-9}
}
Although it is established that apolipoprotein E (APOE) e4 allele increases the risk of Alzheimer's disease (AD), epidemiological studies indicate that genetic risk decreases late in life. This raises the question of whether the effects of APOE on cognition that are seen in midlife arise from a cognitive phenotype of APOE or from the presence of early AD in some APOE-e4 carriers. The authors addressed this question by comparing the cognitive consequences of variation in the APOE gene between… CONTINUE READING

From This Paper

Topics from this paper.
10 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…