The influence of antisense gene location on target gene suppression in the fission yeast Schizosaccharomyces pombe.

Abstract

A fission yeast model was employed to investigate the influence of antisense gene location on the efficacy of antisense RNA-mediated target gene suppression. Fission yeast transformants were generated that contained the target lacZ gene at a fixed position and a single copy antisense lacZ gene integrated into various genomic locations, including the same… (More)

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