The influence of alendronate on spine fusion in an osteoporotic animal model.

@article{Nakao2011TheIO,
  title={The influence of alendronate on spine fusion in an osteoporotic animal model.},
  author={Shin-ichi Nakao and Akihito Minamide and Mamoru Kawakami and Scott D. Boden and Munehito Yoshida},
  journal={Spine},
  year={2011},
  volume={36 18},
  pages={1446-52}
}
STUDY DESIGN A posterolateral lumbar fusion model in osteoporotic rats. OBJECTIVE.: To assess the effect of alendronate on spine fusion in an osteoporotic animal model. SUMMARY OF BACKGROUND DATA The effect of alendronate on spine fusion is still controversial. Also, there are no studies using an osteoporotic animal model to assess the effect of alendronate on spine fusion. METHODS Forty-six female Sprague-Dawley rats underwent either sham-operation (sham) (N = 24) or bilateral ovariectomy… CONTINUE READING
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