The influence of age and dietary conditions on diabetes in the db mouse

@article{Wyse1970TheIO,
  title={The influence of age and dietary conditions on diabetes in the db mouse},
  author={Beatrice M. Wyse and William E. Dulin},
  journal={Diabetologia},
  year={1970},
  volume={6},
  pages={268-273}
}
The mutant mouse, C 57 BL/KsJ -db, develops spontaneous diabetes with many symptoms similar to those observed in the diabetic human. Food intake, body weight, and plasma insulin in thedb mouse were increased by 4 weeks of age and blood sugar by 7 weeks. The blood sugar continued to increase with age but by 3 months plasma insulin, pancreatic insulin, and body weight decreased despite continued elevated food intake. Blood sugar and plasma insulin could be stabilized and pancreatic insulin… CONTINUE READING
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