The influence of advanced glycation endproducts (AGE) on the expression of human endothelial adhesion molecules.

@article{Kunt1998TheIO,
  title={The influence of advanced glycation endproducts (AGE) on the expression of human endothelial adhesion molecules.},
  author={Thomas K. Kunt and Thomas Forst and Oliver Harzer and G Buchert and A Pf{\"u}tzner and Mirjam L{\"o}big and Albrecht R. Zsch{\"a}bitz and Eckart Stofft and Martin Engelbach and J{\"o}rg Beyer},
  journal={Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association},
  year={1998},
  volume={106 3},
  pages={183-8}
}
Advanced glycation endproducts (AGEs) possibly play a dominant role in the pathogenesis of macrovascular disease in diabetes. Recent studies could demonstrate that glycated albumin (AGE-BSA) was able to stimulate vascular cell adhesion molecule-1 (VCAM.1) on endothelial cells. The aim of this study was to find out if AGE-BSA was not only able to enhance the expression of vascular cell adhesion molecule-1, but also of intercellular adhesion molecule-1 (ICAM-1) and E-Selectin on human endothelial… CONTINUE READING
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