The influence of STAT5 antisense oligodeoxynucleotides on the proliferation and apoptosis of selected human cutaneous T-cell lymphoma cell lines

@article{BakiewiczMasiuk2006TheIO,
  title={The influence of STAT5 antisense oligodeoxynucleotides on the proliferation and apoptosis of selected human cutaneous T-cell lymphoma cell lines},
  author={Magdalena Baśkiewicz-Masiuk and Mieczysław Walczak and Ryszard Grzegrz{\'o}łka and Danuta Rogowska and Bogusław Machaliński},
  journal={Archives of Dermatological Research},
  year={2006},
  volume={297},
  pages={450-458}
}
STAT5 (signal transducers and activators of transcription) are suggested to play a role in the pathogenesis of leukaemia and lymphoma; however, their influence on the growth of cutaneous T-cell lymphoma cells is not clear enough. The aim of our study was to analyse the function of STAT5 proteins in the proliferation and apoptosis of selected cutaneous T-cell lymphoma cell lines (HUT 78; PB-1; HUT 102B), using antisense oligodeoxynucleotide (ODN) strategy. RT-PCR and Western blot were applied to… CONTINUE READING