The influence of NMDA receptors in the dorsomedial striatum on response reversal learning.

@article{Palencia2004TheIO,
  title={The influence of NMDA receptors in the dorsomedial striatum on response reversal learning.},
  author={Carlos A. Palencia and Michael E. Ragozzino},
  journal={Neurobiology of learning and memory},
  year={2004},
  volume={82 2},
  pages={81-9}
}
In mammals, the dorsomedial striatum is one brain area shown to be critical for the flexible shifting of response patterns. At present, the neurochemical mechanisms that underlie learning during a shift in response patterns are unknown. The present study examined the effects of NMDA competitive antagonist, DL-2-amino-5-phosphonopentanoic acid (AP-5), injected into the dorsomedial striatum on the acquisition and reversal of a response discrimination. Male Long-Evans rats were tested across two… CONTINUE READING

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