The influence of Lyn kinase on Na,K-ATPase in porcine lens epithelium.

@article{Bozulic2004TheIO,
  title={The influence of Lyn kinase on Na,K-ATPase in porcine lens epithelium.},
  author={Larry D. Bozulic and William L. Dean and Nicholas A. Delamere},
  journal={American journal of physiology. Cell physiology},
  year={2004},
  volume={286 1},
  pages={
          C90-6
        }
}
Na,K-ATPase is essential for the regulation of cytoplasmic Na+ and K+ levels in lens cells. Studies on the intact lens suggest activation of tyrosine kinases may inhibit Na,K-ATPase function. Here, we tested the influence of Lyn kinase, a Src-family member, on tyrosine phosphorylation and Na,K-ATPase activity in membrane material isolated from porcine lens epithelium. Western blot studies indicated the expression of Lyn in lens cells. When membrane material was incubated in ATP-containing… CONTINUE READING

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