The influence of 3,3',5-triiodo-L-thyronine on human haematopoiesis.

  title={The influence of 3,3',5-triiodo-L-thyronine on human haematopoiesis.},
  author={Katarzyna Grymuła and Edyta Paczkowska and Violetta Dziedziejko and Magdalena Baśkiewicz-Masiuk and Miłosz Piotr Kawa and Bartłomiej Baumert and Zbigniew Celewicz and Elżbieta Gawrych and Bogusław Machaliński},
  journal={Cell proliferation},
  volume={40 3},
OBJECTIVES Thyroid hormones mediate many physiological and developmental functions in humans. The role of the 3,3',5-triiodo-L-thyronine (T3) in normal human haematopoiesis at the cellular and molecular levels has not been determined. In this study, it was revealed that the human haematopoietic system might be directly depended on T3 influence. MATERIALS AND METHODS We detected the TRalpha1 and TRbeta1 gene expression at the mRNA level in human cord blood, peripheral blood and bone marrow… CONTINUE READING