The influence of 1,25-dihydroxycholecalciferol on the mineral content of foetal guinea pigs.

@article{Durand1983TheIO,
  title={The influence of 1,25-dihydroxycholecalciferol on the mineral content of foetal guinea pigs.},
  author={Denys Durand and J. P. Barlet and G D Braithwaite},
  journal={Reproduction, nutrition, developpement},
  year={1983},
  volume={23 2a},
  pages={235-44}
}
The influence of 1,25-dihydroxycholecalciferol (0.05 microgram/kg bw/day, given I.M. for 10 days) on calcium transfer from dam to foetus and on foetal calcium and phosphate content was observed in 3 groups of 10 guinea pigs, one group on each of days 40, 50 and 66 of gestation. At 40 and 50 days of gestation, 1,25-dihydroxycholecalciferol increased the calcium and phosphate content of the foetus. 45Ca transfer from the dam to placenta (measured during a 30-90 min period) was higher in treated… CONTINUE READING