The inflammatory response in the CNS.

  title={The inflammatory response in the CNS.},
  author={V Hugh Perry and P B Andersson},
  journal={Neuropathology and applied neurobiology},
  volume={18 5},
In recent years it has been recognized that cells of the mononuclear phagocyte lineage, macrophages and microglia, are a major component of gliosis. We review here studies on the kinetics of the myelomonocytic response to acute excitotoxin induced neuronal degeneration and following the injection of endotoxin (LPS) into the parenchyma of the central nervous system. These studies have shown that the kinetics of myelomonocytic recruitment to the parenchyma of the central nervous system is quite… CONTINUE READING

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