The inflammatory marker serum eosinophil cationic protein (ECP) compared with PEF as a tool to decide inhaled corticosteroid dose in asthmatic patients.

@article{Lwhagen2002TheIM,
  title={The inflammatory marker serum eosinophil cationic protein (ECP) compared with PEF as a tool to decide inhaled corticosteroid dose in asthmatic patients.},
  author={Olle L{\"o}whagen and Aurystella M. Wever and Mirco Lusuardi and Gianna Moscato and Wilfried A. De Backer and L. Gandola and Claudio Ferdinando Donner and Staffan Ahlstedt and L H Larsson and Stephen T. Holgate},
  journal={Respiratory medicine},
  year={2002},
  volume={96 2},
  pages={
          95-101
        }
}
The objective of this study was to compare the inflammatory marker eosinophil cationic protein (ECP) with peak expiratory flow (PEF) in determining the therapeutic needs of inhaled corticosteroids in asthma patients assessed as asthma symptoms. A randomized, single-blind study over 6 months was performed at six specialist centres in Europe. In total, 164 adult patients with moderate to severe symptomatic asthma and regular use of inhaled corticosteroids were included. After a run-in period of 2… CONTINUE READING
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