The inflammatory biomarker YKL-40 as a new prognostic marker for all-cause mortality in patients with heart failure.

@article{Harutyunyan2012TheIB,
  title={The inflammatory biomarker YKL-40 as a new prognostic marker for all-cause mortality in patients with heart failure.},
  author={Marina J Harutyunyan and Michael Christiansen and Julia Sidenius Johansen and Lars Valeur K{\o}ber and Christian Torp-Petersen and Jens Kastrup},
  journal={Immunobiology},
  year={2012},
  volume={217 6},
  pages={
          652-6
        }
}
BACKGROUND Despite progress in management of patients with heart failure (HF) these patients still have a poor prognosis. We tested the hypothesis whether the inflammatory biomarker YKL-40 alone or in combination with high-sensitivity C-reactive protein (hs-CRP) and/or N-terminal-pro-B natriuretic peptide (NT-proBNP) could be a new prognostic biomarker for all-cause mortality in patients with HF. METHODS AND RESULTS A total of 717 of the 1000 patients with severe left ventricular systolic… CONTINUE READING