The inflammasome: firing up innate immunity.


This article introduces a series of reviews covering Inflammasomes appearing in Volume 265 of Immunological Reviews. Innate immunity provides a first line of defense against invading pathogens. The host cell is equipped with a set of germline-encoded pattern-recognition receptors (PRRs) that recognizes the basic structural units that make up microorganisms… (More)
DOI: 10.1111/imr.12297

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