The infection of Harmonia axyridis by a parasitic nematode is mediated by entomopathogenic bacteria and triggers sex-specific host immune responses

  title={The infection of Harmonia axyridis by a parasitic nematode is mediated by entomopathogenic bacteria and triggers sex-specific host immune responses},
  author={T. Gegner and T. Carrau and A. Vilcinskas and Kwang-Zin Lee},
  journal={Scientific Reports},
The harlequin ladybird Harmonia axyridis is native to Asia but has been introduced into many countries as a biological control agent. It is now considered an invasive pest, threatening the biodiversity of native ladybirds globally, in part because of its superior immune system. H. axyridis is infected and killed by the parasitic nematode Parasitylenchus bifurcatus, which could therefore be developed as a biological strategy to counter the spread of this insect pest. However, effective control… Expand
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Pathogens associated with invasive or introduced insects threaten the health and diversity of native species.
  • A. Vilcinskas
  • Biology, Medicine
  • Current opinion in insect science
  • 2019
Whether the factors driving the loss of insect diversity include invasive and/or introduced insects transmitting pathogens to less-resistant native species and the co-introduction of entomopathogens whose spillover is difficult to control is considered. Expand


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Comparative transcriptomics in three ladybird species supports a role for immunity in invasion biology
It is shown that microsporidia carried by the invasive ladybird Harmonia axyridis can kill the native ladybird Adalia bipunctata following the oral uptake of spores, suggesting that their horizontal transmission via intraguild predation may help the invader to outcompete its native competitor. Expand
A switch from constitutive chemical defence to inducible innate immune responses in the invasive ladybird Harmonia axyridis
This work demonstrates that H. axyridis beetles differs from other insects by reducing rather than increasing the antimicrobial activity of its haemolymph following the injection of bacteria, and suggests that bacterial challenge induces innate immune responses associated with the synthesis of immunity-related proteins. Expand
Interactions between the fungal pathogen Beauveria bassiana and three species of coccinellid: Harmonia axyridis, Coccinella septempunctata and Adaliabipunctata
This paper compares the susceptibility of three species of coccinellid, H. axyridis (cultures derived from Japan and UK), Coccinella septempunctata and Adalia bipunctata to infection by B. bassiana and discusses the potential for control of H. Expand
Expansion of the antimicrobial peptide repertoire in the invasive ladybird Harmonia axyridis
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Harmonine, a defence compound from the harlequin ladybird, inhibits mycobacterial growth and demonstrates multi-stage antimalarial activity
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Parasitylenchus bifurcatus n. sp. (Tylenchida: Allantonematidae) parasitizing Harmonia axyridis (Coleoptera: Coccinellidae)
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