The induction of trimethoprim resistance encoded by the type IV dihydrofolate reductase gene.

Abstract

The effect of plasmid pUK1123, which confers low level resistance to trimethoprim when tested on solid minimal medium, but also no resistance when tested on IsoSensitest agar, was investigated in liquid media. The growth of Escherichia coli J62-2, harbouring pUK1123, was unaffected in liquid minimal medium containing trimethoprim 10 mg/L. However, in… (More)

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@article{Young1993TheIO, title={The induction of trimethoprim resistance encoded by the type IV dihydrofolate reductase gene.}, author={Honesty Young and Calum Thomson and Sebastian G. B. Amyes}, journal={Journal of medical microbiology}, year={1993}, volume={38 4}, pages={256-61} }