The induction of second trimester abortions using an intra-amniotic injection of urea and prostaglandin E2.


Induction of 2nd-trimester abortion in 31 patients in England is described. An intraamniotic injection of 80g urea was administered after ensuring a free flow of amniotic fluid. The injection was followed by 5mg PGE2 (prostaglandin E2) injected into the amniotic cavity. The procedure was successful in 30 of the 31 patients, requiring a mean injection-to… (More)