The induction of mutants in a non-acid-fast strain ofMycobacterium phlei with nitrous acid

@article{Konk2008TheIO,
  title={The induction of mutants in a non-acid-fast strain ofMycobacterium phlei with nitrous acid},
  author={J. Kon{\'i}{\vc}{\'e}k and I. M{\'a}lek},
  journal={Folia Microbiologica},
  year={2008},
  volume={15},
  pages={48-53}
}
  • J. Koníčék, I. Málek
  • Published 2008
  • Biology, Medicine
  • Folia Microbiologica
  • The inactivation and mutagenic effets of nitrous acid on a non-acid-fast strain ofMycobacterium phlei were studied. It was found that 0.017m NaNO2 at pH 4.4 may be used for the induction of auxotrophic mutants, scotochromogenic and achromogenic mutants and STM-resistant mutants. Three doubly auxotrophic mutants, three mutants requiring amino acids and three mutants depending on vitamins were obtained. One mutant was not classified. Eighteen scotochromogenic mutants were isolated, seventeen of… CONTINUE READING
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