The induction of host resistance to tick infestation with a salivary gland antigen.

@article{Wikel1981TheIO,
  title={The induction of host resistance to tick infestation with a salivary gland antigen.},
  author={Stephen K. Wikel},
  journal={The American journal of tropical medicine and hygiene},
  year={1981},
  volume={30 1},
  pages={284-8}
}
  • Stephen K. Wikel
  • Published 1981 in
    The American journal of tropical medicine and…
Salivary gland antigen, SGA, derived from partially engorged female Dermacentor andersoni was shown to be capable of inducing resistance to tick infestation in guinea pigs never previously exposed to ticks. Immunization regimens involved the administration of SGA by different routes and with or without the use of adjuvants. Induced resistance was expressed by significantly fewer larvae engorging, and the weight of larvae which did engorge was reduced. Salivary gland antigen has been shown to… CONTINUE READING

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