The induction of cytotoxicity, oxidative stress, and genotoxicity by root canal sealers in mammalian cells.

@article{Camargo2009TheIO,
  title={The induction of cytotoxicity, oxidative stress, and genotoxicity by root canal sealers in mammalian cells.},
  author={Carlos Henrique Ribeiro Camargo and Samira Esteves Afonso Camargo and M{\'a}rcia Carneiro Valera and Karl-Anton Hiller and Gottfried Schmalz and Helmut Schweikl},
  journal={Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics},
  year={2009},
  volume={108 6},
  pages={952-60}
}
OBJECTIVE Toxicologic aspects of the root canal sealers Acroseal, Epiphany, AH Plus, and castor oil polymer (COP) were analyzed using cell culture techniques. STUDY DESIGN Set materials were extracted in culture medium, and cytotoxicity and the generation of reactive oxygen species (ROS) were determined in human pulp cells. The formation of micronuclei… CONTINUE READING