The induction of cardioangitis by Lactobacillus casei cell wall in mice. I. The cytokine production from murine macrophages by Lactobacillus casei cell wall extract.

@article{OkitsuNegishi1996TheIO,
  title={The induction of cardioangitis by Lactobacillus casei cell wall in mice. I. The cytokine production from murine macrophages by Lactobacillus casei cell wall extract.},
  author={Shoko Okitsu-Negishi and Isao Nakano and Katsuya Suzuki and Shintaro Hashira and Tohru Abe and Kohichiro Yoshino},
  journal={Clinical immunology and immunopathology},
  year={1996},
  volume={78 1},
  pages={30-40}
}
A single intraperitoneal injection of the water-soluble cell wall extract from Lactobacillus casei (LCWE) in mice can induce acute inflammatory heart involvement such as cardiac arteritis, similar to the heart lesions in Kawasaki disease. To clarify whether inflammatory cytokines participate in pathogenic mechanisms of LCWE-induced cardioangitis in mice, we studied in vitro cytokine production (IL-1, TNF alpha, and IL-6) from peritoneal macrophages (M phi) stimulated with LCWE in comparison… CONTINUE READING

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