The increase of microRNA-21 during lung fibrosis and its contribution to epithelial-mesenchymal transition in pulmonary epithelial cells

@inproceedings{Yamada2013TheIO,
  title={The increase of microRNA-21 during lung fibrosis and its contribution to epithelial-mesenchymal transition in pulmonary epithelial cells},
  author={Mitsuhiro Yamada and Hiroshi Kubo and Chiharu Ota and Toru Takahashi and Yukiko Tando and Takaya Suzuki and Naoya Fujino and Tomonori Makiguchi and Kiyoshi Takagi and Takashi Suzuki and Masakazu 9 Ichinose},
  booktitle={Respiratory research},
  year={2013}
}
BACKGROUND The excess and persistent accumulation of fibroblasts due to aberrant tissue repair results in fibrotic diseases such as idiopathic pulmonary fibrosis. Recent reports have revealed significant changes in microRNAs during idiopathic pulmonary fibrosis and evidence in support of a role for microRNAs in myofibroblast differentiation and the epithelial-mesenchymal transition in the context of fibrosis. It has been reported that microRNA-21 is up-regulated in myofibroblasts during… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 31 references

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

The Journal of experimental medicine • 2010
View 20 Excerpts
Highly Influenced

Participation of miR-200 in pulmonary fibrosis.

The American journal of pathology • 2012
View 2 Excerpts

Interferon-γ production by neutrophils during bacterial pneumonia in mice.

American journal of respiratory and critical care medicine • 2011
View 1 Excerpt

Inhibition and role of let-7d in idiopathic pulmonary fibrosis.

American journal of respiratory and critical care medicine • 2010
View 3 Excerpts

Similar Papers

Loading similar papers…