The increase in mitochondrial DNA copy number in the tissues of gamma-irradiated mice.

Abstract

Changes in the number of mitochondrial DNA (mtDNA) copies in the brain and spleen tissues of gamma-irradiated (3 Gy) mice were studied by comparative analysis of the long-extension PCR products of mtDNA (15.9 kb) and a fragment of the cluster nuclear beta-globin gene (8.7 kb) amplified simultaneously in one and the same test-tube within total DNA. The… (More)

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@article{Malakhova2005TheII, title={The increase in mitochondrial DNA copy number in the tissues of gamma-irradiated mice.}, author={Ludmila Malakhova and Vladimir G Bezlepkin and Valeria Antipova and Tat'yana Ushakova and Ludmila Fomenko and Nikolai Sirota and Azhub I. Gaziev}, journal={Cellular & molecular biology letters}, year={2005}, volume={10 4}, pages={721-32} }