The inclusion complexes of hesperetin and its 7-rhamnoglucoside with (2-hydroxypropyl)-beta-cyclodextrin.

  title={The inclusion complexes of hesperetin and its 7-rhamnoglucoside with (2-hydroxypropyl)-beta-cyclodextrin.},
  author={Silvana Tommasini and Maria Luisa Calabr{\'o} and Rosanna Stancanelli and Paola Di Donato and Cristina Tom{\'a}s da Costa and Stefania Catania and Valentina Villari and Paola Ficarra and Rita Ficarra},
  journal={Journal of pharmaceutical and biomedical analysis},
  volume={39 3-4},
The effect of (2-hydroxypropyl)-beta-cyclodextrin (HP-beta-CyD) on the solubility properties and spectroscopic features of hesperetin and its 7-rhamnoglucoside, hesperidin, was qualitatively and quantitatively investigated in water, by means of UV-vis absorption and fluorescence spectroscopy. The stoichiometric ratios and stability constants describing the extent of formation of the complexes have been determined by phase-solubility measurements; in both cases type-A(L) diagrams have been… CONTINUE READING

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