The inactivation of some plant viruses by urea.

@article{Bawden1940TheIO,
  title={The inactivation of some plant viruses by urea.},
  author={Frederick Charles Bawden},
  journal={The Biochemical journal},
  year={1940},
  volume={34 8-9},
  pages={
          1258-77
        }
}
  • F. C. Bawden
  • Published 1 September 1940
  • Biology, Medicine
  • The Biochemical journal
OF the simple organic substances known to affect proteins in neutral solution, urea has been the most extensively studied. There-is no obvious reason for this, for urea is neither a more powerful denaturing agent nor a better protein solvent than some of the others. The fact that it is a normal metabolic product is not really relevant, for most of the effects studied are observed only at 10 or more times the physiological concentration. Detailed studies on the action of urea have been made only… Expand
INACTIVATION AND DENATURATION OF PLANT VIRUSES.
  • W. Price
  • Biology, Medicine
  • Advances in virus research
  • 1963
TLDR
The chapter discusses on the kinetics of thermal inactivation of the ribonucleic acid (RNA) of tobacco mosaic virus (TMV) and the denaturation by chemicals. Expand
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The destruction of the ability of PR8 influenza A virus to agglutinate chicken red blood cells was shown to be a complex reaction, the early stages of which proceeded very rapidly and the later stages ofWhich progressed at the same rate as the denaturation of the virus characteristic particles. Expand
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Bushy stunt virus was degraded extensively to produce slowly sedimenting material together with small amounts of more rapidly sedimenting materials and the molecular weight of the protein subunit produced was 6 × 104 and the intact virus particles were composed of about 120 such units along with the ribonucleic acid. Expand
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  • N. Pirie
  • Biology, Medicine
  • Advances in virus research
  • 1957
TLDR
This chapter explores those aspects of tobacco mosaic virus that help in interpreting the structure of the particle and suggests that there are several types of protein in TMV and that they differ in the avidity with which they associate with nucleic acid after the particle has disintegrated. Expand
Potato virus diseases: Review of literature 1941
TLDR
Evidence was obtained that the degree of resistance to one is directly proportional to the amount of the other present, and evidence was secured that four viruses-tobacco mosaic, potato X, tomato bushy stunt, and tobacco necrosis--were irreversibly denatured by urea. Expand
pH-Dependent urea sensitivity of southern bean mosaic virus.
TLDR
The behavior of southern bean mosaic virus (SBMV) virions in urea was markedly pH dependent and revealed several novel features and under conditions where SBMV was somewhat destabilized with urea, increase in the temperature or ionic concentration caused virion precipitation without any detectable degradation. Expand
The Effect of Urea in Counteracting the Influence of Carbohydrates on the pH of dEntal Plaques
It is generally believed that dental caries is initiated by the formation of acid from carbohydrate foods by bacterial "plaques" growing on tooth surfaces. While studying the effect of carbohydratesExpand
On the mechanism of enzyme action. 70. Urea denaturation of trypsin and acyltrypsins.
TLDR
Trypsin and its acetyl and succinyl derivatives were exposed to urea solutions of various concentrations and the resulting changes are due to denaturation, both reversible and irreversible, and to self-digestion. Expand
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