The inactivation of desoxyribonuclease by electron bombardment, deuteron bombardment and heat.

  title={The inactivation of desoxyribonuclease by electron bombardment, deuteron bombardment and heat.},
  author={C. Smith},
  journal={Archives of biochemistry and biophysics},
  volume={45 1},
  • C. Smith
  • Published 1 July 1953
  • Chemistry, Medicine
  • Archives of biochemistry and biophysics
Abstract Experiments on the inactivation of desoxyribonuclease by deuteron and electron bombardment are described, and it is deduced that the sensitive volume of the molecule is a sphere of radius ca . 27 A. and molecular weight 62,000. This means that one primary ionization produced anywhere within the molecule causes its inactivation. Heat inactivation, when dry, gives values for δ H ‡ of 16.000 cal./mole, and for δ S ‡ of −37 cal./mole ∘K. The disorganization of the molecule, if any, is much… Expand
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