The in vivo chromosome constitution of marrow from 34 human leukemias and 60 nonleukemic controls.

A survey of chromosome patterns in human leukemia was aimed at determining: departures from diploidy in different types of acute and chronic leukemia, influence of therapy on chromosome constitution, frequency of aneuploidy in freshly aspirated marrow compared with the same sample after short-term tissue culture. Exact chromosome counts were obtained in… CONTINUE READING