The in vitro response of osteoblasts to bioactive glass.

  title={The in vitro response of osteoblasts to bioactive glass.},
  author={Takashi Matsuda and John E. Davies},
  volume={8 4},
Osteoblasts from neonate rat calvaria migrated in culture from the endocranial surface of parietal bones onto fragments of bone-bonding 45S5 glass or non-bone-bonding quartz glass. These organ culture units were maintained for up to 4 wk. No significant production of extracellular matrix (ECM) was seen on the quartz glass samples. However, osteoblasts colonized the 45S5 samples in multilayers and produced abundant ECM as seen by light (LM), scanning electron (SEM) and transmission electron (TEM… CONTINUE READING