The in vitro regulation of ovarian follicle development using alginate-extracellular matrix gels.

@article{Kreeger2006TheIV,
  title={The in vitro regulation of ovarian follicle development using alginate-extracellular matrix gels.},
  author={Pamela K. Kreeger and Jason W Deck and Teresa K. Woodruff and Lonnie D Shea},
  journal={Biomaterials},
  year={2006},
  volume={27 5},
  pages={714-23}
}
The extracellular matrix (ECM) provides a three-dimensional structure that promotes and regulates cell adhesion and provides signals that direct the cellular processes leading to tissue development. In this report, synthetic matrices that present defined ECM components were employed to investigate these signaling effects on tissue formation using ovarian follicle maturation as a model system. In vitro systems for follicle culture are being developed to preserve fertility for women, and cultures… CONTINUE READING