The in vitro and in vivo cytotoxicity of menadione (vitamin K3) against rat transplantable hepatoma induced by 3'-methyl-4-dimethyl-aminoazobenzene.

@article{Su1991TheIV,
  title={The in vitro and in vivo cytotoxicity of menadione (vitamin K3) against rat transplantable hepatoma induced by 3'-methyl-4-dimethyl-aminoazobenzene.},
  author={W C Su and Te Ping Sun and Felicia Y-H Wu},
  journal={Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences},
  year={1991},
  volume={7 9},
  pages={454-9}
}
Menadione (vitamin K3, 2-methyl-1,4-naphthoquinone) is a synthetic derivative of napthoquinone. Its ability to inhibit cell growth in a wide variety of and human tumor cell types, and in rat hepatocytes has been recognized. Using a rat transplantable hepatoma model, we have evaluated the cytotoxic activity of menadione in hepatoma cells. Tumor cells in… CONTINUE READING