The importance of the recognition of benign ethnic neutropenia in black patients during treatment with clozapine: case reports and database study

  title={The importance of the recognition of benign ethnic neutropenia in black patients during treatment with clozapine: case reports and database study},
  author={Eromona Whiskey and Olubanke Olofinjana and David Taylor},
  journal={Journal of Psychopharmacology},
  pages={842 - 845}
Clozapine is the treatment of choice in refractory schizophrenia. Its more extensive use is limited by adverse effects and the need for regular blood monitoring. However, black patients are disadvantaged with respect to clozapine usage. Lower baseline Absolute Neutrophil Count compared with Whites leads to a greater frequency of blood testing, treatment interruptions and discontinuation. This may in part be explained by Benign Ethnic Neutropenia, but too few black patients are thus registered… 

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Clozapine, agranulocytosis, and benign ethnic neutropenia

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    Postgraduate Medical Journal
  • 2005
This editorial looks at the important issues associated with agranulocytosis and BEN in patients receiving clozapine, a atypical antipsychotic effective in treatment resistant schizophrenia.

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