The importance of surgical margins in primary malignancies of the liver.

Abstract

Resection is an important treatment modality for hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). Anatomic resection is generally preferred for HCC. When anatomic resection is not feasible, prospective data have demonstrated an improved outcome among HCC patients who have a resection with wide versus narrow surgical margins. Similarly, among patients with ICC, R1 resection has been associated with worse outcomes. In addition, margin width may also impact risk of recurrence and survival. As such, provided adequate functional liver remnant remains, anatomic resection with wide margins is recommended for HCC and ICC.

DOI: 10.1002/jso.24123

Cite this paper

@article{Lafaro2016TheIO, title={The importance of surgical margins in primary malignancies of the liver.}, author={Kelly J. Lafaro and Miral Sadaria Grandhi and Joseph M. Herman and Timothy M Pawlik}, journal={Journal of surgical oncology}, year={2016}, volume={113 3}, pages={296-303} }