The importance of repairing stalled replication forks

@article{Cox2000TheIO,
  title={The importance of repairing stalled replication forks},
  author={Michael M. Cox and Myron F. Goodman and Kenneth N. Kreuzer and David J. Sherratt and Steven J. Sandler and Kenneth J. Marians},
  journal={Nature},
  year={2000},
  volume={404},
  pages={37-41}
}
The bacterial SOS response to unusual levels of DNA damage has been recognized and studied for several decades. Pathways for re-establishing inactivated replication forks under normal growth conditions have received far less attention. In bacteria growing aerobically in the absence of SOS-inducing conditions, many replication forks encounter DNA damage, leading to inactivation. The pathways for fork reactivation involve the homologous recombination systems, are nonmutagenic, and integrate… 
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