The importance of mitochondria in age-related and inherited eye disorders.

@article{Jarrett2010TheIO,
  title={The importance of mitochondria in age-related and inherited eye disorders.},
  author={Stuart Gordon Jarrett and Alfred S Lewin and Michael Boulton},
  journal={Ophthalmic research},
  year={2010},
  volume={44 3},
  pages={
          179-90
        }
}
Mitochondria are critical for ocular function as they represent the major source of a cell's supply of energy and play an important role in cell differentiation and survival. Mitochondrial dysfunction can occur as a result of inherited mitochondrial mutations (e.g. Leber's hereditary optic neuropathy and chronic progressive external ophthalmoplegia) or stochastic oxidative damage which leads to cumulative mitochondrial damage and is an important factor in age-related disorders (e.g. age-related… CONTINUE READING

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