The importance of integrin-linked kinase in the regulation of bladder cancer invasion.

@article{Matsui2012TheIO,
  title={The importance of integrin-linked kinase in the regulation of bladder cancer invasion.},
  author={Yoshiyuki Matsui and K. J. S. Assi and Osamu Ogawa and Peter A. Raven and Shoukat Dedhar and Martin E. Gleave and Baljinder Salh and Alan I So},
  journal={International journal of cancer},
  year={2012},
  volume={130 3},
  pages={521-31}
}
It is important to understand the molecular mechanisms of bladder cancer progression not only to prevent cancer progression but also to detect new therapeutic targets against advanced bladder cancer. The integrin-linked kinase (ILK) is a major signaling integrator in mammalian cells and plays an important role in epithelial-mesenchymal transition (EMT) of human cancers, but its mechanisms are not completely understood. In this study, we investigated the importance and mechanisms of ILK in… CONTINUE READING