The importance of genetic factors for the development of arthropathy: a longitudinal study of children and adolescents with haemophilia A.

Abstract

Haemophilia A is a congenital bleeding disorder characterised by recurrent haemorrhages into the major joints. Haemophilic arthropathy is a well-established outcome of recurrent joint bleeding; however, it is clear that multiple factors determine the extent and severity of its occurrence. We sought to identify genetic factors related to abnormalities in… (More)
DOI: 10.1160/TH16-06-0440

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