The importance of de novo mutations for pediatric neurological disease--It is not all in utero or birth trauma.

Abstract

The advent of next generation sequencing (NGS, which consists of massively parallel sequencing to perform TGS (total genome sequencing) or WES (whole exome sequencing)) has abundantly discovered many causative mutations in patients with pediatric neurological disease. A surprisingly high number of these are de novo mutations which have not been inherited… (More)
DOI: 10.1016/j.mrrev.2015.12.002

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Cite this paper

@article{Erickson2016TheIO, title={The importance of de novo mutations for pediatric neurological disease--It is not all in utero or birth trauma.}, author={Robert P. Erickson}, journal={Mutation research. Reviews in mutation research}, year={2016}, volume={767}, pages={42-58} }