The importance of being aromatic: π interactions in sodium symporters.

Abstract

In the LeuT family of sodium solute symporters, 13-17% of the residues in transmembrane domains are aromatic. The unique properties of aromatic amino acids allow them to play specialized roles in proteins, but their function in membrane transporters is underappreciated. Here we analyze the π bonding pattern in the LeuT (5TMIR) family and then describe the… (More)
DOI: 10.1021/bi301329w

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Cite this paper

@article{Jiang2012TheIO, title={The importance of being aromatic: π interactions in sodium symporters.}, author={Xuan Jiang and Donald D. F. Loo and Bruce A. Hirayama and Ernest M Wright}, journal={Biochemistry}, year={2012}, volume={51 47}, pages={9480-7} }