The importance of age and smoking in evaluating adverse cytogenetic effects of exposure to environmental agents.

@article{Tucker1996TheIO,
  title={The importance of age and smoking in evaluating adverse cytogenetic effects of exposure to environmental agents.},
  author={James D. Tucker and D Helen Moore},
  journal={Environmental Health Perspectives},
  year={1996},
  volume={104},
  pages={489 - 492}
}
Fluorescence in situ hybridization with chromosome-specific composite DNA probes (chromosome painting) is a reliable and efficient method for detecting structural chromosome aberrations. Painting is now being used to quantify chromosome damage in many human populations. In one such study we evaluated 91 unexposed people ranging in age from birth (cord bloods) to 79. We established a baseline frequency of stable aberrations that showed a highly significant curvilinear increase with age (p < 0… CONTINUE READING

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