The importance of HLA genes to susceptibility in the development of juvenile diabetes mellitus. A study of 93 patients and 68 first degree blood relations.

@article{Ludwig1977TheIO,
  title={The importance of HLA genes to susceptibility in the development of juvenile diabetes mellitus. A study of 93 patients and 68 first degree blood relations.},
  author={Heinz Ludwig and Guntram Schernthaner and Wolfgang Mayr},
  journal={Diabete & metabolisme},
  year={1977},
  volume={3 1},
  pages={43-8}
}
The importance of genetically determined antigens of the HLA system in etiology and pathogenesis of juvenile onset diabetes (JOD) was studied in 93 JOD-patients and 68 blood relations. A close association was found between JOD and B-locus antigens B8 and Bw15, and C-locus antigen Cw3. Patients positive for one of these antigens have a 2-3 times -- and those… CONTINUE READING