The importance of G-protein beta lambda subunits.

  title={The importance of G-protein beta lambda subunits.},
  author={Jorge A. I{\~n}iguez-Lluh{\'I} and Christiane Kleuss and Alfred G. Gilman},
  journal={Trends in cell biology},
  volume={3 7},
As the properties of more and more isoforms of the molecules involved in G-protein-mediated signal transduction pathways are unravelled, surprising diversity and versatility are being revealed. The path from receptor to effector is not dictated exclusively by the alpha subunits of heterotrimetric G proteins. The nature of the beta lambda subunit complex probably controls interactions of G(alpha) with receptors. In addition, dissociation of G(alpha)-GTP from G(beta lambda)provides two signalling… CONTINUE READING

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